Project Summary/Abstract The UROBIOME 2020 Conference, led by Linda Brubaker, MD will be held at the University of California San Diego (UCSD) on March 5 2020 in conjunction with an International meeting of UCSD's Center for Microbiome Innovation (March 3-4, 2020), led by a world-renown microbiome researcher, Rob Knight PhD. The human urobiome is a rapidly growing area of scientific research that may inform prevention, diagnosis and treatment of multiple benign urologic conditions of interest to the NIDDK and other NIH institutes. The recent discovery of the urobiome has opened opportunities for additional scientific investigations that can refine the current body of evidence for these conditions. However, there are few investigators trained to participate in the team-based approach necessary for quality urobiome research. The UROBIOME 2020 Conference will bring together leaders in the field to share their expertise and connect with interested investigators who are new to urobiome research. Drs. Brubaker and Knight have formed a collaboration designed to broaden the breadth and depth of urobiome work, regionally, nationally and internationally. Conference goals include connecting individuals interested in urobiome research to the larger, established international group of microbiome experts. The UROBIOME 2020 Conference will also provide training and mentorship to a cadre of competitively-selected junior investigators who will receive modest travel awards from this R13 Conference Grant. Small group sessions and workshops will help individuals make the most of publically available resources that can advance urobiome research.